Can surgical intervention improve pressure injury healing rates?

Six-month healing rates with traditional wound care are 45% for stage III & 31% for stage IV.28
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The challenges of managing late-stage pressure injuries:

Contamination & chronic inflammation
Significant tissue loss
Compromised healing and complex patients

Why is Myriad an optimal ECM graft for late-stage pressure injuries (PIs)?

  • Can help fill surgical dead space and reduce the risk of a seroma or hematoma formation2-3,5,11
  • Modulates wound proteases to counter inflammation12
  • Tolerates bacterial contamination1-5,11
  • Can be used as a single application to assist with cost savings1-3

Volumetric tissue infill of a chronic PI

Healing via traditional wound care can be a slow process, and may not be realistic in some cases due to the involvement of deeper tissues and exposed structures.

Read this case study of a paraplegic patient with an extensive 6-month-old PI.

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Pre-operative
Pre-operative
Intra-operative myriad placement
Intra-operative myriad placement
Day 10
Day 10
4 Weeks
4 Weeks
6.5 Weeks
6.5 Weeks
9 Weeks
9 Weeks

Algorithm helps guide approach to PI surgical reconstruction

The published algorithm aims to reduce complications and improve outcomes with recommendations for adjunctive therapies including NPWT and use of Myriad as the bioscaffold of choice.

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Surgical Reconstruction of Stage 3 and 4 Pressure Injuries: A Literature Review and Proposed Algorithm from an Interprofessional Working Group

  • Adv Skin Wound Care. 2023;36(5):249-258.
  • Awad SS, Stern JD, Milne CT, Dowling SG, Sotomayor R , Ayello EA, Aguirre LJF, Khalaf BZ, Gould LJ, Desvigne MN, Chaffin AE

Watch our recent webinar on demand

Learn more about the publication of an algorithmic approach to surgical reconstruction of PIs with case study examples.

White paper now available

Surgical management of stage 3 and 4 PIs: A standardized approach

This resource discusses the challenges of managing late-stage PIs, and summarizes a recently published algorithm which standardizes the approach to surgical management.
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Pressure Injury case studies

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Initial Defect

Flap Advancement and Closure

Myriad Matrix™

Application in a Stage IV Pressure Injury of the Ischium and Greater Trochanter

Abigail E. Chaffin MD, FACS, CWSP, MAPWCA

View case study
CC.0207

Pre-operative Assessment

Day 36

Myriad Morcells™

Application in a Bilateral Heel Pressure Injury

Michael Cormican, MD

View case study
CC.0167

Pre-operative

Week 9

Myriad Matrix™
Endoform™ Antimicrobial
Endoform™ Natural

Volumetric Tissue Infill of a Chronic Pressure Injury

Bariqa Salah M.D. and Heba Daradka

View case study
CC.0051