Limb salvage is worth the fight
5-year mortality rates are poor following limb amputation (ranging from 53%-100%)27
Lower extremity reconstruction can be complex & challenging
Co-morbidities and compromised circulation
Contamination
Exposed avascular and vital structures
Myriad can help address the challenges of lower extremity reconstruction and promotes functional tissue regeneration.
Myriad enables functional tissue formation in three key ways:
Rapid coverage and fill over exposed and avascular structures1-3
Watch Dr. Chaffin discuss Myriad Matrix™ application in reconstruction resulting from fibromatosis of the plantar foot.

Persists in the defect despite contamination and inflammation1-4,7,8
Watch Dr. Geiger discuss Myriad Matrix™ application in necrotizing soft tissue infection.

Cost-effective utilization with a median of one product application1-3
Watch Dr. LaLama discuss Myriad Morcells™ and Myriad Matrix™ application in a chronic lower extremity wound.

Limb salvage in a DFU with exposed bone and osteomyelitis
Read this case study about Myriad’s use in the reconstruction of a complex DFU in a patient with multiple comorbidities.

Intra-operative

No recurrence at one year follow-up
NEW STUDY
100% tissue coverage and fill in 30* days with no infections1
In the largest real-world study of lower extremity reconstructions, Myriad delivered exceptional value at $253.90 (USD)** per defect.
- 130 lower extremity defects in 120 patients
- Minimal exclusion criteria
- Patients at a high risk of amputation
*Median 30.0 days (IQR: 26.9, 33.1) **Median product cost
Limb Salvage via Surgical Soft-tissue Reconstruction With Ovine Forestomach Matrix Grafts: A Prospective Study
- Plastic & Reconstructive Surgery-Global Open 12(12):p e6406, December 2024.
- Lawlor, John DPM; Bosque, Brandon A. DPM; Frampton, Christopher PhD; Young, D. Adam PhD; Martyka, Patrick DPM
AROA ECM™
Our foundation technology
Derived from ovine forestomach, the AROA ECM technology is a patented platform for our soft tissue repair and reconstruction portfolio. It regenerates functional tissue, enabling clinicians to achieve more for patients.