Application in a Chronic Venous Leg Ulcer
Anthony J. LaLama, DPM
Podiatric Surgeon – Premier Foot & Ankle. Ascension Providence Hospital – Southfield, MI
Week 0
Week 11
Results
- ~95% epithelialized at 11 weeks
- Minimal drainage and no complications
- Single application of Myriad
- Closed via secondary intention with standard dressings
Patient details
47-year-old male
Medical history
Venous insufficiency, hypertension
Case details
- Description: Full thickness painful venous leg ulcer of the right lateral leg
- Wound Age: 2 years
- Prior failed treatments had included amnion grafts, skin substitutes/CTPs, compression, and multiple debridements
- Approximate Size: 10.4 cm x 13.7 cm x 0.6 cm
Application photos
Week 0
- Sharp, excisional debridement
- Applied Myriad Morcells (500 mg) to wound bed, then applied Myriad Matrix (10 x 10 cm, 3-Layer), rehydrated in sterile saline
- Secondary dressing: Non-adherent contact layer, hydrofiber dressing, and Unna boot
Week 4
- Pain significantly improved
- Noted budding of granulation tissue
- Residual Myriad noted in wound bed
- No complications
- Continue with compression and absorbent secondary dressing changed daily or when saturated
Week 5
- Pain continues to improve
- Continued budding of viable granulation tissue
- No complications
- Plan to epithelialize via secondary intention. Continue with compression and absorbent secondary dressing changed daily, or when saturated
Week 7
- Minimal discomfort remains
- Approximately 80% epithelialized
- Significant decrease in drainage
- No complications
Week 10
- Approximately 90% epithelialized
- Minimal drainage
- No complications
- Continue with compression and absorbent secondary dressing changed daily
Week 11
- Approximately 95% epithelialized, with one small area unhealed (arrow)
- Minimal drainage and no complications
- Plan to close via secondary intention with standard wound dressings
Results may vary. Dr. LaLama has a consultancy agreement with Aroa Biosurgery.
