Symphony outcomes supported by a new Randomized Controlled Trial
A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People with Diabetes: A Randomized Controlled Trial
Wagner Grade
1 & 2 DFUs
143
Wounds
10
Sites
Key Findings
More DFUs completely healed with Symphony + SOC at 12 weeks than SOC alone.
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Complete Closure Rate at 12 Weeks
Complete closure rates at 12 weeks. 55% Symphony + SOC vs 35% SOC alone. A relative increase of 57%. Adjusted PP analysis: p=0.039*, n=109
Reduction in mean time to heal with Symphony + SOC vs SOC alone.
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Mean Time to Complete Wound Closure
65.4 Days Symphony + SOC vs 73.2 Days SOC alone. PP: p=0.041*, n=109
A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People with Diabetes: A Randomized Controlled Trial
David G. Armstrong, Dennis P. Orgill, Robert D. Galiano, John C. Lantis, Alexander M. Reyzelman, Robert J. Snyder, Adam L. Isaac, Marissa J. Carter, Charles M. Zelen
Explore the RCT behind Symphony
Discover how the study was designed, who took part and what the findings may mean for diabetic foot wound care.
Case Studies from the RCT
Application of Symphony + SOC in a Wagner Grade 2 DFU of the Forefoot
Rapid closure in a high‑risk forefoot ulcer.
Application of Symphony + SOC in a Wagner Grade 1 DFU of the Hallux
Complete epithelialization in 4 weeks.
